[BioC] Differences between lmfit model(from limma package) and Illumina-custom Model (from GenomeStudio)

Gordon K Smyth smyth at wehi.EDU.AU
Fri Apr 26 06:04:30 CEST 2013


Dera Abdul,

We use GenomeStudio in order to export probe summary profiles and control 
summary profiles which are then read into the limma package.

GenomeStudio doesn't do any downstream statistical analysis, as far as I 
know, comparable to limma. To see what limma does, see the User's Guide:

http://www.bioconductor.org/packages/release/bioc/vignettes/limma/inst/doc/usersguide.pdf

Best wishes
Gordon

> Date: Thu, 25 Apr 2013 10:20:58 +0530
> From: Abdul Rawoof <abdul87.edu at gmail.com>
> To: bioconductor at r-project.org
> Subject: [BioC] Differences between lmfit model(from limma package)
> 	and Illumina-custom Model(from GenomeStudio).
>
> Hello everybody,
>
> I am doing WG-DASL data analysis using GenomeStudio and R/Bioconductor.
> Could anyone please able to tell me the major differences in both model
> that affect the result.
> If any documentation available please tell me.
>
> Thanks,
> Abdul Rawoof
>

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