[BioC] DESeq estimateDispersions

[Simon Anders]

Hi

On 17/04/13 17:32, Lucia Peixoto wrote:
> Error in parametricDispersionFit(means, disps) :
>    Parametric dispersion fit failed. Try a local fit and/or a pooled
> estimation. (See '?estimateDispersions')
[...]
> PS: This is not "traditional" RNA-seq data, each row is a window in the
> genome and the values on the matrix are mapped reads in each sample for
> each window

The parametric fit fails sometimes, especially on non-standard data 
sets. This is why we offer the local fit as a fall-back.

   Simon