[BioC] EdgeR :column sums of counts or library size?

[anna [guest]]

Dear all,
I was wondering wether it would change the results if we provide the initial library size, the mapped reads number or just the sum of counts to perform an RNAseq analysis,
thanks in advance,
anna

 -- output of sessionInfo(): 

R version 2.15.1 (2012-06-22)
Platform: i386-pc-mingw32/i386 (32-bit)

locale:
[1] LC_COLLATE=French_France.1252  LC_CTYPE=French_France.1252   
[3] LC_MONETARY=French_France.1252 LC_NUMERIC=C                  
[5] LC_TIME=French_France.1252    

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] edgeR_3.0.0  limma_3.14.1


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