[BioC] Use probesets with highest baseline expression for differntial gene expression in LIMMA

[Ekta [guest]]

Hello All, 
I am relatively new to R and bioconductor. I would like to know if there is a way to alter LIMMA defualt options such that the package instead of averaging signal intensities of probesets selects the probesets with highest baseline 
expression/signal intensity? 
 
Any help would be greatly appreciated. 



 -- output of sessionInfo(): 

> sessionInfo()
R version 2.9.1 (2009-06-26) 
i386-pc-mingw32 

locale:
LC_COLLATE=English_India.1252;LC_CTYPE=English_India.1252;LC_MONETARY=English_India.1252;LC_NUMERIC=C;LC_TIME=English_India.1252

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] limma_2.18.3

--
Sent via the guest posting facility at bioconductor.org.