[BioC] meta-analysis with RankProd

[Maciej Jończyk]

Hi Barbara,

> Can I just log2-transform the normalised intensity in the one channel
> data sets and compare them like that?

I advise you to transform your log2 data to probability of expression 
scale (POE, available in metaArray and poe packages).

see paper Ramasamy A, Mondry A, Holmes CC, Altman DG (2008) Key issues 
in
conducting a meta-analysis of gene expression microarray datasets. PLoS 
Med 5(9):
e184. doi:10.1371/journal.pmed.0050184.

I've found it useful.

Best Wishes,
Maciej

-- 
Maciej Jonczyk,
Department of Plant Molecular Ecophysiology
Faculty of Biology, University of Warsaw
02-096 Warsaw, Miecznikowa 1
Poland



-- 
This email was Anti Virus checked by Astaro Security Gateway. http://www.astaro.com