[BioC] RNA-seq data simulation

[Mark Robinson]

You could start with rnbinom().  The 'size' argument is 1/dispersion.

Mark

On 21.08.2012, at 16:51, Alpesh Querer wrote:

> I should mention I want to use negative binomial as underlying distribution.
> 
> Thanks.
> Al
> 
> On Tue, Aug 21, 2012 at 9:41 AM, Alpesh Querer <alpeshq at gmail.com> wrote:
> 
>> Hi all,
>> 
>> I want to simulate counts for 1000 genes for 5 RNA-seq samples (with 3
>> biological replicates each), and I want to provide the dispersion
>> parameters myself.
>> Is there a package or code that can help me do this?
>> 
>> Thanks a lot for your help,
>> Al
>> 
> 
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Bioinformatics
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