[BioC] multifactorial analysis

Gordon K Smyth smyth at wehi.EDU.AU
Wed Apr 11 01:02:42 CEST 2012


Dear Andreia,

See

McCarthy et al, Differential expression analysis of multifactor RNA-Seq 
experiments with respect to biological variation. Nucleic Acids Research, 
28 January 2012.

http://nar.oxfordjournals.org/content/early/2012/02/06/nar.gks042

Best wishes
Gordon

> Date: Mon, 9 Apr 2012 12:06:46 +0100
> From: Andreia Fonseca <andreia.fonseca at gmail.com>
> To: bioconductor <bioconductor at stat.math.ethz.ch>, <sanders at fs.tum.de>
> Subject: [BioC] multifactorial analysis
>
> Hello,
>
> I am planning an experiment to profile miRNAs by ngs with the following
> multifactorial design: breed, tissue type, diet, tissue color. Is it
> possible with DEXSeq to account with the effect of interaction between
> these factors?
> Thanks.
>
> Andreia
>
> -----------------------------------------------------------------------------------------------
> Andreia J. Amaral, PhD
> BioFIG - Center for Biodiversity, Functional and Integrative Genomics
> Instituto de Medicina Molecular
> University of Lisbon
> Tel: +352 217500000 (ext. office: 28253)
> email:andreiaamaral at fm.ul.pt ; andreiaamaral at fc.ul.pt

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