[BioC] biomaRt and HapMap

Steffen Durinck durinck.steffen at gene.com
Fri Jul 22 19:51:56 CEST 2011


Hi Deidre,

It looks like there is some issue with HapMap in the BioMart central
repository.  You might want to do your query using the hapmap web
interface at:

http://hapmap.ncbi.nlm.nih.gov/biomart/martview/

Cheers,
Steffen

On Fri, Jul 22, 2011 at 5:58 AM, Deidre <deidre.krupp at duke.edu> wrote:
> I need to get SNP data from HapMap via biomaRt, but am having trouble
> getting any results from any query of the hapmap_rel27 dataset.  For
> example, both of the following:
>
> HM <- useMart("HapMap_rel27","hm27_variation_ceu")
> ceu <- getBM(
> c("chrom","start","strand","marker1"),
> filters=c("chrom"), values="chr22",HM)
> )
>
> hapmap <- useMart("HapMap_rel27", dataset="hm27_variation_yri")
> yri <-
> getBM(c("chrom","start","alleles","ref_allele","ref_allele_freq","other_allele_freq",filters=c("chrom","coding_nonsynon"),values=list("chr19",TRUE),mart=hapmap)
>
> result in an empty table such as:
>
>  > head(yri)
> [1] chrom             start             alleles
> ref_allele        ref_allele_freq   other_allele_freq
> <0 rows> (or 0-length row.names)
>
> I've tried with both biomaRt 2.8.1 and 2.9.2.  Queries to marts ensembl
> or snp work as expected.  Am I missing a detail in my queries to HapMap,
> or is there an issue with the mart?
>
> Regards,
> Deidre
>
>
>  > sessionInfo()
> R version 2.13.0 (2011-04-13)
> Platform: i386-pc-mingw32/i386 (32-bit)
>
> locale:
> [1] LC_COLLATE=English_United States.1251  LC_CTYPE=English_United
> States.1252    LC_MONETARY=English_united States.1252
> [4] LC_NUMERIC=C                           LC_TIME=English_United
> States.1252
>
> attached base packages:
> [1] stats    graphics  grDevices utils    datasets methods  base
>
> other attached packages:
> [1] biomaRt_2.9.2
>
> loaded via a namespace (and not attached):
> [1] RCurl_1.6-6.1 tools_2.13.0 XML_3.4-0.2
>
>        [[alternative HTML version deleted]]
>
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