[BioC] what is the correct way of normalizing 3 different U133 platforms using RMA?

[James W. MacDonald]

An almost identical question was asked and answered today, so I would 
point you to the archives:

https://stat.ethz.ch/pipermail/bioconductor/2011-August/040726.html

Best,

Jim



On 8/15/2011 3:09 PM, Jack Luo wrote:
> I have a bunch of cel files profiled on U133A, U133A2 and U133plus2.
> Obviously, in order to combine them, I'll only focus on the common probes
> shared by the 3 different platforms. However, I am not sure what is the
> correct way of RMA normalizing them. Should cel files from the same platform
> RMA normalized separately, or they can be RMA normalized by only focusing on
> the common probe sets?
>
> Thanks,
>
> -Jack
>
> 	[[alternative HTML version deleted]]
>
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-- 
James W. MacDonald, M.S.
Biostatistician
Douglas Lab
University of Michigan
Department of Human Genetics
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