[BioC] what is the correct way of normalizing 3 different U133 platforms using RMA?

James W. MacDonald jmacdon at med.umich.edu
Mon Aug 15 21:16:42 CEST 2011

An almost identical question was asked and answered today, so I would 
point you to the archives:




On 8/15/2011 3:09 PM, Jack Luo wrote:
> I have a bunch of cel files profiled on U133A, U133A2 and U133plus2.
> Obviously, in order to combine them, I'll only focus on the common probes
> shared by the 3 different platforms. However, I am not sure what is the
> correct way of RMA normalizing them. Should cel files from the same platform
> RMA normalized separately, or they can be RMA normalized by only focusing on
> the common probe sets?
> Thanks,
> -Jack
> 	[[alternative HTML version deleted]]
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James W. MacDonald, M.S.
Douglas Lab
University of Michigan
Department of Human Genetics
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Ann Arbor MI 48109-5618
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