[BioC] Limma, eBayes different sample size of groups and adjustment

[Naomi Altman]

You do not need to correct for the different sizes.  The analysis 
self-corrects.

Naomi Altman

At 09:54 AM 4/27/2011, you wrote:
>Dear BC list,
>
>I am using limma the first time.
>I have an unbalanced sample with 130 controls and 60 cases, should I
>correct for the different sizes?
>My idea is to take only 60 of my 130 controls. How u handle this problem?
>
>And is there a special method to correct/adjust my sample for example
>smoking status or weight?
>
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