[BioC] microRNA: which genes code for a specific mirna?

[Robinson, Peter]

Hi Tim,

I don't think this is a Bioconductor specific problem.

In any case, what do you mean? "hsa-mir-21" is the gene that encodes for
"hsa-miR-21". What do you want to obtain? Some miRNAs are contained in
protein coding transcripts, but not all...



The genename for this miRNA is simply MIR21, see http://www.genenames.org/data/hgnc_data.php?hgnc_id=HGNC:31586.
But in the literature generally the same name (e.g., miR-21) seems to be used for the gene, the precursor, the primary, and the mature microRNA. It might be useful to read this article for some background on microRNA metabolism if you havent done so already:

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-4BJK582-F&_user=10&_coverDate=01%2F23%2F2004&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=ab04c8721417798295b966e6af5dc599

best wishes Peter






Cheers,

Cei

Tim Smith wrote:
> Hi,
>
> I wanted to know which gene encodes a particular miRNA. I tried the CORNA and microRNA packages. Although these give which miRNA targets which gene, I couldn't find which gene encodes an miRNA mapping.
> Is there any way that I can go about doing this (e.g. to find which gene encodes for hsa-mir-21)?
> many thanks
>
>
>
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>
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