[BioC] How to normalize one additional CEL file?

Christian Ruckert cruckert at uni-muenster.de
Thu Aug 12 15:38:33 CEST 2010


See bioconductor package RefPlus for an implementation of the RMA 
normalization which stores normalization parameters for later use on 
additional samples.

Greetings,
Christian


Am 12.08.2010 15:20, schrieb Wiktor Mazin:
> Dear List,
>
> Suppose you normalize a training set in some way (RMA, etc) to build a
> predictor and then want to apply this predictor to a test set consisting of
> only 1 CEL file (actually, you may have several test set CEL files but you
> have to preprocess and predict them individually).
>
> How can you preprocess / normalize 1 (test set) CEL file using the same
> normalization settings used for the training set? (NB! Training and test set
> may not be normalized together)
> Are there some functions / packages for this purpose, or would you suggest
> some other way of resolving this?
>
> Looking forward to your reply.
>
> best regards,
> Wiktor Mazin
>
> 	[[alternative HTML version deleted]]
>
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