[BioC] dealing with missing values in microarray data set

Amit Kumar amitkumartiwary at gmail.com
Sun Oct 4 11:42:55 CEST 2009

Hi! All,

I am trying to analyze very large microarray data sets with 550
arrays. But there are lots of missing values (NA) in the data set
which is making my life difficult.
So I need to get rid of those NAs in the data. I do not want to
impute. Also, I can not remove those rows containing NAs as almost
each row have it.
Is it a good idea to replace NAs with zero in the data set. If yes,
why? and if not, why not? Your suggestion will be invaluable.


More information about the Bioconductor mailing list