[BioC] 转发: Statistical approach to compare differentiall expressed gene lists

qinghua xu xy0702cy at yahoo.com.cn
Wed Dec 23 07:24:04 CET 2009


Dear all,
 
I have identified two lists of differential expressed gene from the same expression data but treated with different normalisation methods. List A contains 995 genes and list B contains 2400 genes. More than nine hundreds genes are overlapped between two lists, namely most of genes in list A are also included in list B. The idea is to check whether list B is better than list A.
 
In addition to visualisation approach (like hierarchical clustering heatmap) or biological interpretations,  I am wondering is there any other statistical approach available to compare two differential expressed gene lists?
 
I would appreciate any advice, or pointers to any references for this!
 
Bests,
Qinghua



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