[BioC] Gostats with Yeast annotation
Alex Gutteridge
alexg at ruggedtextile.com
Tue Jul 22 15:37:14 CEST 2008
Hi,
I've been trying to use the hyperGTest method from the GOstats package
with some yeast ORF data. I notice in this thread from a month or so
ago that there are problems at the moment with using any of the yeast
annotation sets apart from 'YEAST' (which is deprecated) due to
missing ID2EntrezID methods:
https://stat.ethz.ch/pipermail/bioconductor/2008-June/022697.html
I just wanted to make sure that this was still the case and I guess
fish around for an estimated ETA for when the org.Sc.sgd.db
annotations (which are replacing YEAST as I understand it) will be
compatible with hyperGTest?
Also, is the exact source of GO annotations used in these packages
documented anywhere? Looking in the DESCRIPTION file I see 'primarily
based on mapping using ORF identifiers from SGD' for org.Sc.sgd.db and
'assembled using data from public data repositories' for YEAST. Should
I just take it these are based on the SGD GO annotation file from the
date given in the Packaged field of the DESCRIPTION file? For YEAST
there is also a Created field which is aprox. 1 month prior to the
Packaged date so I'm guessing the real age of the data is that one?
The yeast annotations change so quickly it's useful to be able to pin
this down as accurately as possible.
Thanks in advance for any help with these questions.
Alex Gutteridge
Department of Biochemistry
University of Cambridge
More information about the Bioconductor
mailing list