[BioC] weighting chips

Sean Davis sdavis2 at mail.nih.gov
Tue Jul 1 15:12:40 CEST 2008


On Tue, Jul 1, 2008 at 8:10 AM, DAVID ARTETA GARCIA
<darteta001 at ikasle.ehu.es> wrote:
> Dear list,
>
> some packages provide functions that allow weighting of the chips, as is the
> case for normalize.quantiles.robust {affy}, by including a vector of
> weights. I cannot find information as to how or why to weight chips in an
> experiment.
> On what basis do people weight chips? is it something the investigator has
> to set beforehand or does it depend on quality of chips? are weight values
> any values in the range of 0-1?
>
> I would be grateful if you could shed some light on this and/or direct me to
> any publications or webpages.

Hi, David.

See this thread for some thoughts on array weights.

http://thread.gmane.org/gmane.science.biology.informatics.conductor/18638

Sean



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