[BioC] General normalization problem that's *similar* to microarrays.

Alex Bokov bokov at uthscsa.edu
Sat Dec 6 16:36:18 CET 2008


Yes, it makes a great difference-- for A/B normalized there is much less 
variability than for (A normalized)/(B normalized) and a lot more 
proteins making the significance threshold.
> Dear Alex
>
> have you checked whether it actually makes a difference - and if so, 
> in what way?
>
>
> Best wishes
>      Wolfgang
>
> ----------------------------------------------------
> Wolfgang Huber, EMBL-EBI, http://www.ebi.ac.uk/huber
> .
>



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