[BioC] gene expression data help

[Sean Davis]

Srinivas Iyyer wrote:
> Dear group, 
>
> i have a expression data matrix ( after RMA) with
> samples belonging to one cancer type (all
> adeno-carcinoma samples from gut and no normal or
> other type)
>
> how can i get genes that show variability across all
> samples. 
>
> is this a non-parametric estimation and should i be
> doing annova?
>   

You might try filtering by CV (which is just standard deviation/mean) if 
you are using single-channel data or by standard deviation if you are 
using common reference 2-channel data. 

Sean