[BioC] RMA on a Data frame or a matrix

Kasper Daniel Hansen khansen at stat.Berkeley.EDU
Fri Sep 7 19:31:59 CEST 2007


On Sep 6, 2007, at 12:51 PM, Khan, Sohail wrote:

> Dear List,
>
> I was wondering if RMA function can be applied to a data frame or a  
> matrix??
> Thanks.

What exactly do you mean by that. For the entire algortihm  
(background correction, normalization and summarization) you need to  
keep track of probesets - ie. groups of probes targeting the same  
gene. This is only really necessary for the summarization though.  
Where do you have such information? You can certainly hack the  
functions to work and the background correction and normalization  
works without problem on a matrix - did you check?

Kasper



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