[BioC] About ndups error chol(V)

[Gordon Smyth]

Dear Kevin,

You have given us so little information that you can't really expect 
anyone on this list to be able to tell you what your problem is. You 
haven't even told us exactly what the error message is.

You also need to tell us your session information, sessionInfo(). 
Please read the posting guide on the Bioconductor website.

I am guessing that the Choleski decomposition is failing because your 
regression problem is singular. This could possibly arise because 
cor$consensus=1, or perhaps because you have MA$weights which are 
close to zero. There's no way for us to know this. You will need to 
do some more exploration of your data yourself.

Best wishes
Gordon

>Date: Mon, 29 Oct 2007 16:46:32 +0800
>From: " ?? " <zhaoye07 at gmail.com>
>Subject: [BioC] About ndups error chol(V)
>To: bioconductor at stat.math.ethz.ch
>
>Dear all,
>
>I'm using the oligo microarray to find expression different genes. I decided
>to use limma. This array have 3 spots for each gene.
>But when I input the command
>"fit<-lmFit(MA,design,ndups=3,correlation=cor$consensus)", It complains an
>error on chol(V).
>It works if I don't use ndups, but I need this. So, can you help me to solve
>this problem?
>
>best wishes
>
>kevin