[BioC] Expression levels of individual affymetrix probes

[Johnstone, Alice]

Hi,
Is it possible to apply the transformations used on the probesets to
individual probe expression?  Such as RMA and fitting to a lm to obtain
your list of probesets of interest.  Then potentially looking at
individual probe expression levels across samples for all 11 probes of
that probeset?  (but normalized across samples to enable greater
accuracy of the eyeball-o-meter)
The reason behind this pondering is to investigate further transcript
variant effects, and also to better match qpcr investigations to the
location of the probe which shows the greatest change...
Cheers,
Alice 


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