[BioC] segmentation aCGH data

Sean Davis sdavis2 at mail.nih.gov
Wed Oct 10 18:18:24 CEST 2007


jhs1jjm at leeds.ac.uk wrote:
> Hi Sean,
> 
> As its 2 colour so I'm looking at relative amounts wouldn't that mean I
> wouldn't see copy number variants, would they not be in both my
> samples? 

I forgot to answer this question, directly.  If the reference genome and
the test genome contain the same number of copies of a CNV region, you
will not see it, as you suggest.  However, if your reference and test
samples contain different numbers of copies, then this will potentially
be evident in your data.

Sean



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