[BioC] Chromosome 23 and 24 dropped after run snapCGH processCGH

J-C. Marioni jcm68 at hermes.cam.ac.uk
Wed Oct 3 19:44:17 CEST 2007


Hi Caimiao,

If you set the argument maxChromThreshold equal to 24, this should prevent 
chromosomes 23 and 24 being excluded from the MA object.

Hope this helps,
John

On Wed, 3 Oct 2007, caiwei at mdanderson.org wrote:

> Dear list,
>
> I am using snapCGH to look at Agilent's mouse aCGH array.  my MAlist object
> (MA1) have chromosomes 1-19, 23 and 24.  After I run the processCGH
> function, chromosome 23 and 24 are no longer in my new MAlist object (MA2).
>
> Any idea where the problem is?  Thanks!
>
>
> __________________________
> Caimiao Wei, Ph.D.
>
> Senior Statistical Analyst
> Division of Quantitative Sciences
> UT M.D.Anderson Cancer Center
> 1515 Holcombe Blvd, Unit 237
> Houston, TX 77030-4009
>
> Tel: (713)563-4297
> Fax: (713) 792-4262
> Office location: HMB13. 200A
>
>
>
>> table(MA1$genes$Chr)
>
>    1     2     3     4     5     6     7     8     9    10    11    12
> 13
> 16283 16856 13062 13658 13977 14156 13570 11538 12058 11879 12658 10443
> 10693
>   14    15    16    17    18    19    23    24
> 10836  9357  9090  9122  8092  6405 12089   612
>
>> MA2<-processCGH(MA1, method.of.averaging=NULL, ID='ProbeName')
>> table(MA2$genes$Chr)
>
>    1     2     3     4     5     6     7     8     9    10    11    12
> 13
> 16283 16856 13062 13658 13977 14156 13570 11538 12058 11879 12658 10443
> 10693
>   14    15    16    17    18    19
> 10836  9357  9090  9122  8092  6405
>> sessionInfo()
> R version 2.5.1 (2007-06-27)
> sparc-sun-solaris2.9
>
> locale:
> C
>
> attached base packages:
> [1] "splines"   "grid"      "tools"     "stats"     "graphics"
> "grDevices"
> [7] "utils"     "datasets"  "methods"   "base"
>
> other attached packages:
>      xtable      snapCGH         aCGH          sma     multtest
> cluster
>     "1.4-6"      "1.4.0"     "1.10.0"     "0.5.15"     "1.16.0"
> "1.11.7"
>        GLAD          aws      DNAcopy  tilingArray       pixmap
> geneplotter
>    "1.10.0"    "1.3-3.1"     "1.10.0"     "1.14.0"      "0.4-7"
> "1.14.0"
>     lattice     annotate   genefilter     survival          vsn
> strucchange
>   "0.15-11"     "1.14.1"     "1.14.1"       "2.32"      "2.2.0"
> "1.3-2"
>    sandwich          zoo RColorBrewer         affy       affyio
> Biobase
>     "2.0-2"      "1.3-2"      "1.0-1"     "1.14.2"      "1.4.1"
> "1.14.1"
>       limma
>    "2.10.5"
>>
>
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