[BioC] gcrma version differences

Zhijin (Jean) Wu zwu at alexander.stat.brown.edu
Thu Feb 22 22:21:42 CET 2007


I do not remember the exact mapping between  changes  and version numbers. 
But one major change is the estimate of background parameters from a 
windowed quantile to a loess curve.

On Thu, 22 Feb 2007, Karen Vranizan wrote:

> Hello.  I recently re-ran gcrma on my dataset with version 2.6.  Why are the results so different from those I got with version 1.1?  I know there were large changes between 1.0 and 1.1, but I can't find documentation explaining the changes I am seeing with the recent gcrma.  I am using simple gcrma with default arguments.  Could someone direct me to a document that clearly lists the methodological changes that were introduced to the gcrma algorithm for all relevant versions?  Thank you.
>
>
> Karen Vranizan
> Functional Genomics Lab
> 261A Life Sciences Addition
> Mail Code #3200
> UC Berkeley, CA 94720-3200
>
> Phone: 510-642-7520
> Fax:      510-643-2685
> email: vranizan at berkeley.edu
>
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