[BioC] Why "M" values?

Debashis Ghosh ghoshd at umich.edu
Fri Sep 29 22:26:51 CEST 2006


Hi Jenny,

I believe they are called M-values because on a log scale, you are 
taking the difference (M for minus) of the intensity measurements in 
the two channels, i.e. log(Cy5/Cy3) = log(Cy5) - log(Cy3).

Best,
Debashis
-- 
Debashis Ghosh
Associate Professor of Biostatistics
University of Michigan
1420 Washington Heights
Ann Arbor, MI 48109-2029

email: ghoshd at umich.edu
phone: (734) 615-9824
fax: (734) 763-2215


Quoting Jenny Drnevich <drnevich at uiuc.edu>:

> Hi all,
>
> Sorry to abuse the list with this general microarray question, but I was
> hoping someone could quickly help me out with this... why are M-values
> (log2(ratio of expression in A to B)) called M-values?
>
> Thanks,
> Jenny
>
> Jenny Drnevich, Ph.D.
>
> Functional Genomics Bioinformatics Specialist
> W.M. Keck Center for Comparative and Functional Genomics
> Roy J. Carver Biotechnology Center
> University of Illinois, Urbana-Champaign
>
> 330 ERML
> 1201 W. Gregory Dr.
> Urbana, IL 61801
> USA
>
> ph: 217-244-7355
> fax: 217-265-5066
> e-mail: drnevich at uiuc.edu
>
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