[BioC] Exclude individual probes before normalization

Jenny Drnevich drnevich at uiuc.edu
Mon Sep 11 17:52:17 CEST 2006


Hi Jim,

Do you know if using the 'subset' argument of rma() has any effect on the 
memory it uses? I'm not sure if it would decrease the memory requirements 
by working with less data, or actually increase it by doing a subsetting 
step somewhere.

Thanks,
Jenny

At 07:37 AM 9/9/2006, James W. MacDonald wrote:
>Dana Wohlbach wrote:
> > Does anyone know of a way to exclude individual probes before
> > normalizing using a method like RMA?  In other words, I have
> > identified certain probes in my CEL files that I don't want included
> > in the normalization procedure.  Is there a way to use Bioconductor
> > to make this happen?
>
>See ?rma(), in particular the 'subset' argument.
>
>Best,
>
>Jim
>
>
> >
> > Thanks,
> > Dana
> >
> > _______________________________________________
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>
>--
>James W. MacDonald
>University of Michigan
>Affymetrix and cDNA Microarray Core
>1500 E Medical Center Drive
>Ann Arbor MI 48109
>734-647-5623
>
>
>
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Jenny Drnevich, Ph.D.

Functional Genomics Bioinformatics Specialist
W.M. Keck Center for Comparative and Functional Genomics
Roy J. Carver Biotechnology Center
University of Illinois, Urbana-Champaign

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