[BioC] Exclude individual probes before normalization

Jenny Drnevich drnevich at uiuc.edu
Mon Sep 11 17:45:29 CEST 2006


Hi Dana,

If you want to remove individual probes instead of entire probesets, see 
the response I sent to Donald Schwartz on this last Friday - it has some 
code to modify the cdf for your chip by removing individual probes and/or 
entire probe sets.

Cheers,
Jenny

At 12:04 PM 9/8/2006, Dana Wohlbach wrote:
>Does anyone know of a way to exclude individual probes before
>normalizing using a method like RMA?  In other words, I have
>identified certain probes in my CEL files that I don't want included
>in the normalization procedure.  Is there a way to use Bioconductor
>to make this happen?
>
>Thanks,
>Dana
>
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Jenny Drnevich, Ph.D.

Functional Genomics Bioinformatics Specialist
W.M. Keck Center for Comparative and Functional Genomics
Roy J. Carver Biotechnology Center
University of Illinois, Urbana-Champaign

330 ERML
1201 W. Gregory Dr.
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e-mail: drnevich at uiuc.edu



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