[BioC] Recommendation for limma?

[Naomi Altman]

I think you are asking whether limma should be used to select 
differentially expressed genes before attempting a multivariate 
method such as factor analysis.

Factor analysis will be limited by the problem of having fewer 
samples than genes.  Hence, preselecting a smaller set of genes is 
definitely helpful.

--Naomi

At 07:52 PM 9/7/2006, Lana Schaffer wrote:
>Greetings,
>I am wondering if it is recommended to reduce the input of gene list 
>from 45,000 genes
>by some criteria before doing factor analysis with limma?
>
>Lana Schaffer
>Biostatistics/Informatics
>The Scripps Research Institute
>DNA Array Core Facility
>La Jolla, CA 92037
>(858) 784-2263
>(858) 784-2994
>schaffer at scripps.edu
>
>
>
>         [[alternative HTML version deleted]]
>
>_______________________________________________
>Bioconductor mailing list
>Bioconductor at stat.math.ethz.ch
>https://stat.ethz.ch/mailman/listinfo/bioconductor
>Search the archives: 
>http://news.gmane.org/gmane.science.biology.informatics.conductor

Naomi S. Altman                                814-865-3791 (voice)
Associate Professor
Dept. of Statistics                              814-863-7114 (fax)
Penn State University                         814-865-1348 (Statistics)
University Park, PA 16802-2111