[BioC] BioC normalisations for small array 2 colour data?

Dan Swan bioinformatics.lists at gmail.com
Thu Sep 7 14:44:35 CEST 2006


I have some data from a small specialised microarray - 200 genes, 1
spiked control, 1 negative control.  This is 2 colour data, with dye
swaps.  I was wondering what an appropriate normalisation for this
scenario is within Bioconductor given that Lowess is unreliable for
<1000 genes?

Any pointers would be gratefully recieved.



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