[BioC] Normalisation GCRMA Error

[Nicolas Servant]

Hi all,

I used GCRMA to normalize 200 arrays HG-U133A with succes. In order to 
avoid the potential memory problemes, i use a R64 bits version (2.31) 
with GCRMA 2.4.1
But when I try to normalize 300 HG-U133-plus2 arrays, I have a 
segmentation fault :

Loading required package: affy
Loading required package: Biobase
Loading required package: tools

Welcome to Bioconductor

    Vignettes contain introductory material. To view, type
    'openVignette()' or start with 'help(Biobase)'. For details
    on reading vignettes, see the openVignette help page.

Loading required package: affyio
Loading required package: gcrma
Loading required package: matchprobes

Computing affinities.Done. *** caught segfault ***
address 0, cause 'memory not mapped'

Traceback:
 1: .Call("read_probeintensities", filenames, rm.mask, rm.outliers,     rm.extra, ref.cdfName, dim.intensity, verbose, cdfInfo, which,     PACKAGE = "affyio")
 2: read.probematrix(filenames = filenames, which = "pm", cdfname = cdfname)
 3: fast.bkg(filenames = filenames, pm.affinities = pm.affinities,     mm.affinities = mm.affinities, index.affinities = index.affinities,     type = type, minimum = minimum, optical.correct = optical.correct,     verbose = verbose, k = k, rho = rho, correction = correction,     stretch = stretch, fast = fast, cdfname = cdfname)
 4: just.gcrma(filenames = l$filenames, phenoData = l$phenoData,     description = l$description, notes = notes, compress = compress,     verbose = verbose, normalize = normalize, bgversion = bgversion,     affinity.info = affinity.info, type = type, k = k, stretch = stretch,     correction = correction, rho = rho, optical.correct = optical.correct,     fast = fast, minimum = minimum, optimize.by = optimize.by,     cdfname = cdfname)
 5: justGCRMA(filenames = filenames, celfile.path = celfile.path,     type = "affinities")
 6: normAffy(files$filenames, celfile.path = dataPath, NormMethod)
aborting ...

The "read_probeintensities" C function seems to have some problemes ...
Does anybody know if the number of arrays is limited in GCRMA ? or why i 
have a segmentation fault !
Thanks,

Best,
Nicolas S.

-- 
Nicolas Servant
Equipe Bioinformatique
Institut Curie 
26, rue d'Ulm - 75248 Paris Cedex 05 - FRANCE

Email: Nicolas.Servant at curie.fr
Tel: 01 53 10 70 55
http://bioinfo.curie.fr/