[BioC] significance of "wrong" clustering of differential genes

Benjamin Otto b.otto at uke.uni-hamburg.de
Tue Nov 14 12:09:08 CET 2006


Hi Naomi,

sorry, probably the image size (37kb) exeeded the 40kb limit together with
the rest of the mail. Here it comes again in higher compression.

Concerning the distance measure I would agree with you. However --that's why
I initially thought to provide the cluster plot-- according the expression
values I DO agree with the clustering result! And that is the point I
wouldn't normally expect from clustering extra determined significant
genes...

Benjamin

-----Ursprüngliche Nachricht-----
Von: Naomi Altman [mailto:naomi at stat.psu.edu] 
Gesendet: 13 November 2006 22:03
An: Benjamin Otto; 'BioClist'
Betreff: Re: [BioC] significance of "wrong" clustering of differential genes

The heatmap did not come through (to me).  However, clustering is highly
dependent on the choice of distance measure.

--Naomi


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