[BioC] Significancy of not differentially expressed genes

[Mohammad Esad-Djou]

Hello Naomi, 

now I have a question.  :)

> >I am looking for a measure of the significance for the potential
> >'not differentially expressed' call that could be given to a gene
> >and that can be considered reliable from the community.

I believe that you can find with multiple Testing (e.g. SAM, siggenes) 'not differentially expressed'  genes. 
If H0 is correct: genes are not differentially expressed. 
did I understand correctly? 
 
I am not sure, but I believe that multiple Testing is helpful. 

Thanks,
Mohammad 

> -----Ursprüngliche Nachricht-----
> Von: Naomi Altman <naomi at stat.psu.edu>
> Gesendet: 09.05.06 23:15:28
> An:  bioconductor at stat.math.ethz.ch
> Betreff: Re: [BioC] Significancy of not differentially expressed genes


> There is not.
> 
> --Naomi
> 
> At 05:36 AM 5/9/2006, Mike Ferker wrote:
> >Dear List,
> >
> >I have quite a big problem but probably a 'naive'
> >question for you.
> >
> >I need to know if there is a good and broadly accepted
> >way to select genes that are not differentially expressed
> >in a microarray experiment.
> >I am looking for a measure of the significance for the potential
> >'not differentially expressed' call that could be given to a gene
> >and that can be considered reliable from the community.
> >
> >I have searched the internet but found just a couple of discussions
> >and papers about selecting control genes (i.e. housekeeping)
> >for real time pcr verification of microarrays results, but
> >nothing more.
> >
> >Thanks
> >
> >Mike
> >
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> 
> Naomi S. Altman                                814-865-3791 (voice)
> Associate Professor
> Dept. of Statistics                              814-863-7114 (fax)
> Penn State University                         814-865-1348 (Statistics)
> University Park, PA 16802-2111
> 
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