[BioC] ad hoc tools for affy tiling arrays?

Kasper Daniel Hansen khansen at stat.Berkeley.EDU
Wed Feb 1 06:35:38 CET 2006


In a a sense tiling arrays are more general tools than expression  
arrays. What you are looking for (and hence your method of analysis)  
is (or at least should be) dependent on your research question. In  
comparison, with an expression array you are interested in genes that  
are DE between different experimental conditions.

/Kasper

On Jan 26, 2006, at 1:36 AM, Dario Greco wrote:

> hi all,
> we are probably going to use affymetrix tiling arrays for human.
> i have understood that in some ways it is possible to use gcrma for  
> image
> preprocessing and that the quantile normalization might be a  
> reasonable
> method.
> but i was wondering if there is (or if there is going to be) any ad  
> hoc tool
> in bioconductor also for the later steps of the analysis and  
> interpretations
> of such experiments.
> any suggestions are warmly appreciated.
> thanks,
>
> greetings
> d
>
> -- 
>
> Dario Greco
>
> Institute of Biotechnology - University of Helsinki
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>
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>
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