[BioC] chip area distortion tolerance

[Thalacker-Mercer, Anna E]

Hello,
I have a question in addition to your question about distortions.  How
much should artifacts influence taking the chip out of the analysis?  I
have several chips that have decent sized artifacts in them, but seem
fine when looking at the RLE and NUSE plots.  

Thanks
Anna

-----Original Message-----
From: bioconductor-bounces at stat.math.ethz.ch
[mailto:bioconductor-bounces at stat.math.ethz.ch] On Behalf Of D.Enrique
ESCOBAR ESPINOZA
Sent: Monday, December 11, 2006 11:27 AM
To: bioconductor at stat.math.ethz.ch
Subject: [BioC] chip area distortion tolerance

Hi,
I am doing some QC for chips,
in the article of HEBER & SICK (2006),
they use a threshold of 20% of distortion of the area chip.

!) is there any consensus?
2) how do you estimate this %percentage of distortion in R?

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