[BioC] aCGH across samples

[Daniel Brewer]

Hi,

In the new year, I am going to start work on a large aCGH dataset from
quite a few different samples.  I am new to CGH analysis.  What I would
like to know the best way to find amplicons or deletions that are shared
in the majority of samples (a statistic would be useful).  More
specifically I would like to find the smallest common differential
regions that contain a known gene.

Any thoughts?

Many thanks

Daniel

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Daniel Brewer, Ph.D.

Institute of Cancer Research
Molecular Carcinogenesis
MUCRC
15 Cotswold Road
Sutton, Surrey SM2 5NG
United Kingdom