[BioC] Microarray analysis with continuous variables

[Sean Davis]

On 8/13/06 9:58 PM, "David K Pritchard" <dpritch at u.washington.edu> wrote:

>      We are currently working on a microarray project where we have to
> correlate both clinical and morphological (MRI) data with human expression
> data.  Much of the data is in the form of continuous variables. While it can
> be turned into the categorical classifications most often used in array
> analysis, we would also like to look for correlations between the continuous
> variables and gene expression patterns.
>       Does anyone on this list know of any good references on this subject?
> Also are there any existing Bioconductor packages which support this kind of
> analysis.

You might want to look at the possibility of applying random forests.  They
can be used for both classification and regression.

Sean