[BioC] strange effect of "half" bkg substraction in Limma
hilmar.berger at imise.uni-leipzig.de
Thu Aug 3 09:31:18 CEST 2006
Steven McKinney schrieb:
> I have not yet come across journal articles investigating
> specific binding (references would be appreciated) to the MM
> probes, but this may be part of the issue. Perhaps it is GC
> related? We will be investigating this issue.
For a discussion of sequence-specific binding to PM and MM probes you
might want to have a look at this publication:
Binder, H., Preibisch, St.
GeneChip microarrays-signal intensities, RNA concentrations and probe
J. Phys.: Condens. Matter 18 (2006) 537-566.
Institut for medical informatics, statistics and epidemiology
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email: hilmar.berger at imise.uni-leipzig.de
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