[BioC] background correction with cDNA array data

Naomi Altman naomi at stat.psu.edu
Thu Oct 27 01:42:28 CEST 2005


Did you want to write your own background correction method?  The 
normalization routines in marray and limma do background correction.

--Naomi

At 04:51 PM 10/26/2005, Qi.Zhang at astrazeneca.com wrote:
>Dear all,
>
>I have searched through the bioconductor ducument and this mailing list, but
>could not find a general guidance about how to correct background in cDNA
>array data.  I have imported my data (GPR files from GenePix) using
>functions from marray.  Now what are the available methods for background
>correction before normalization?  Any suggestions/experience is very much
>appreciated.
>
>Regards,
>
>Qi Zhang
>
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Naomi S. Altman                                814-865-3791 (voice)
Associate Professor
Dept. of Statistics                              814-863-7114 (fax)
Penn State University                         814-865-1348 (Statistics)
University Park, PA 16802-2111



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