[BioC] expresso

Jianping Jin jjin at email.unc.edu
Thu May 5 16:15:28 CEST 2005


Dear Bioconductor:

I ran expresso with the estrogen data set on R2.1.0 (affy 1.5.8-1)installed 
on Windows XP. Normalization with qspline worked fine, but not with loess. 
Any suggestions?

> x <- expresso(data_cel, bgcorrect.method="rma",
+ normalize.method="qspline",
+ pmcorrect.method="pmonly",
+ summary.method="medianpolish")
background correction: rma
normalization: qspline
PM/MM correction : pmonly
expression values: medianpolish
background correcting...done.
normalizing...[1] "samples= 404 k= 5 first= 999"
.
..
.
done.
12625 ids to be processed
|                    |
|####################|

> y <- expresso(data_cel, bgcorrect.method="rma",
+ normalize.method="loess",
+ pmcorrect.method="pmonly",
+ summary.method="medianpolish")
background correction: rma
normalization: loess
PM/MM correction : pmonly
expression values: medianpolish
background correcting...done.
normalizing...Error: NA/NaN/Inf in foreign function call (arg 1)


Any comments will be appreciated!

Jianping Jin



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