[BioC] Genelogic dilution series mixed samples

[Rafael A. Irizarry]

i looked at that data back when i was writing the paper you mention. not
enougn room to include the graphs. here are the relevant pictures:

http://www.biostat.jhsph.edu/~ririzarr/mixture/

the short answer is that it seems to be close to what you expect. what
makes it complicated is that the mixing occurs in the linear scale but the
errors are multiplicative. 


On Mon, 8 Mar 2004, Matthew Hannah wrote:

> Hi,
> 
> Just a quick question. Irizarry et al. analysed the single concentration
> chips from this data set (below). But there are also mixes of 50:50 and 
> 75:25 of the 2 RNA sources. Has the relative linearity of the mixes in 
> comparison to the single concentrations been studied and if so what was
> the outcome (any reference)?
> 
> http://hajek.stat.ubc.ca/~jochen/stat547/DilutionStudy.html
> 
> Thanks,
> Matt
> 
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