[BioC] Limma and missing data

Sean Davis sdavis2 at mail.nih.gov
Mon Mar 1 21:05:36 MET 2004

I have a very noisy data set that I am having trouble thresholding to get
useful genes, so I am resorting to using missing values.  (Yes, I could
impute, but my n is not huge and consists of four non-distinct groups).  My
question is:

How does limma handle missing data?  It doesn't mind NA's coming in, but
does it correct for the different df at each gene given the number of NA's?


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