[BioC] gcrma and other normalizations
Raffaele Calogero
raffaele.calogero at unito.it
Wed Jun 2 07:09:13 CEST 2004
Hi,
if a don't mistake the present implementation of gcrma uses directly the
quantile normalization.
Is there any command to switch off the quantile normalization, or how
can I modify the gcrma function to eliminate the quantile normalization?
Since I would like to see the effect of other normalization procedures
on gcrma, is it a risonable procedure to normalize the data first and
subsequently applying the gcrma intensity calculation, after having
modified the function in orther to remove the quantile normalization?
data<-ReadAffy()
data.invariant<-normalize(data, method="invariantset")
data.gcrma.inv<-gcrma(data) #
Raffaele
--
Prof. Raffaele A. Calogero
Genomics and Bioinformatics Unit
Dipartimento di Scienze Cliniche e Biologiche
c/o Az. Ospedaliera S. Luigi
Regione Gonzole 10, Orbassano
10043 Torino
tel. ++39 0116705410
Lab. ++39 0116705408
Fax ++39 0119038639
e-fax ++39 0112365410
Mobile ++39 3333827080
email: raffaele.calogero at unito.it
www: www.bioinformatica.unito.it
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