[BioC] hclust and (Eisen+ de Hoon) cluster3 program
Tan, MinHan
MinHan.Tan at vai.org
Mon Dec 6 22:25:46 CET 2004
Did you use a correlation distance metric for hclust?
AFAIK, that's what the Eisen software uses. I think the default distance
metric for hclust is Euclidean?
Could be wrong, but it's worth a try.
Min-Han Tan
-----Original Message-----
From: bioconductor-bounces at stat.math.ethz.ch
[mailto:bioconductor-bounces at stat.math.ethz.ch] On Behalf Of Benjamin
Haibe-Kains
Sent: Monday, December 06, 2004 7:10 AM
To: Bioconductor Mailing List
Subject: Re: [BioC] hclust and (Eisen+ de Hoon) cluster3 program
Hi Michael,
I think that the differences are too important to be due to different
implementation decisions. Actually my problem is that I have a group of
1 object and the rest in the other group when I use the 'centroid'
hclust (I use cutree to have the main two groups) and it's not the case
with other softwares. It looks like a bug in the Fortran routine but I
can not access to it.
Have you reported this "bug" before ? Can I write my 'centroid' method
easily ?
cheers,
benjamin
michael watson (IAH-C) wrote:
>Benjamin
>
>You will likely get different results from all clustering software,
>even when using the same parameters. This is because many arbitrary
>decisions have to be made during a hierarchical cluster analysis and
>different programmers will make those decisions in different ways.
>
>Mick
>
>-----Original Message-----
>From: bioconductor-bounces at stat.math.ethz.ch
>[mailto:bioconductor-bounces at stat.math.ethz.ch] On Behalf Of Benjamin
>Haibe-Kains
>Sent: 06 December 2004 11:05
>To: Bioconductor Mailing List
>Subject: [BioC] hclust and (Eisen+ de Hoon) cluster3 program
>
>
>Hi all,
>
>I have a problem with the R function 'hclust'. I have noticed
>differences in clustering when I use the 'centroid' cluster method with
>'hclust' and the cluster3 program (see M. Eisen and M. de Hoon).
>
>Have you noticed some differences too ?
>
>I use
>
>hclust from library 'stats' (Built: R 2.0.1; i386-pc-linux-gnu;
>2004-11-15 15:56:06; unix)
>cluster 3.0 using C Clustering Library version 1.25
>
>Thanks a lot
>
>
>
--
Benjamin Haibe-Kains
[http://www.ulb.ac.be/di/map/bhaibeka/]
PhD student in the Machine Learning Group (MLG)
[http://www.ulb.ac.be/di/mlg/]
Universite Libre de Bruxelles (ULB)
E-mail: bhaibeka at ulb.ac.be
MicroArray Unity
[http://www.bordet.be/servmed/array/index.htm]
Institut Jules Bordet (IJB)
E-mail: benjamin.haibekains at bordet.be
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