[BioC] B statistic in limmaGUI

Sean Davis sdavis2 at mail.nih.gov
Thu Aug 19 14:58:38 CEST 2004


Liz,

B is a lod (logarithm of the odds), so even odds (1:1) are given a 
value of 0.  Better than average is positive and worse is negative.

Sean

On Aug 19, 2004, at 8:43 AM, Elizabeth Brooke-Powell wrote:

> Sean,
>
> Thanks for getting back to me so quickly, just so I follow your 
> explanation,
> the more negative the number i.e. -6 vs -1 the greater the odds of it 
> not
> being expressed? What does having a negative number actually mean in
> relationship to 0 or a positive number?
>
> Thanks again,
>
> Liz
>
> -----Original Message-----
> From: Sean Davis [mailto:sdavis2 at mail.nih.gov]
> Sent: 19 August 2004 13:33
> To: Elizabeth Brooke-Powell
> Cc: Bioconductor
> Subject: Re: [BioC] B statistic in limmaGUI
>
> Liz,
>
> It isn't a measure of data quality.  It is a measure of the likelihood
> of differential expression.  Negative values mean odds are that it is
> not differentially expressed.
>
> Sean
>
>



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