[BioC] Affy package

[Mette A. Peters]

Can someone please explain to me how to interpret the RNA degradation
analysis (plot and slope) in the Affy package. I see little correlation
between the slope calculated with this tool and the 5'/3' signal intensity
ratio of the housekeeping genes (such as GAPDH and Actin) on the Affy
arrays.  What slope is considered an indication of degradation?  Can you
also please explain to me what the p-value refers to.

Thanks,
Mette Peters