[BioC] Affy Normalization!

[Puhong Gao]

Hi, all,

To reduce the data size before quantile normalization, I am thinking to take PM intensity only (to solve memory problem).  Is there a way to separate pm and mm data while the affybatch format is still perserved? If yes, is it appropriate to normalize the data based on the PM values only? Thanks in advance for your inputs.

Data: from 150 u34a chips   Computer: Windows XP pro with 2 GB of RAM

Regards,

Puhong Gao, PhD
Dev. Psychobiology
NYSPI, Unit# 40
1051 Riverside Dr.
New York, NY 10032
(212) 543-5710
	[[alternate HTML version deleted]]