[BioC] (no subject)

[Laurent Gautier]

On Mon, Jun 02, 2003 at 11:46:18PM -0400, Rafael A. Irizarry wrote:
> 
> 
> On Mon, 2 Jun 2003 alea at interfree.it wrote:
> 
> > 
> >  Laurent Gautier <laurent at cbs.dtu.dk> wrote:
> > 
> > > One should keep in mind the assumption behind many of the normalization
> > > techniques: "most of the genes are not differentially expressed across
> > > the
> > > experiments". Filtering before normalization/scaling should be done with
> > > that in mind.
> > 
> > Hi all.
> > I'm a novice,... may be this is he reason why I'm loosing myself..
> > What is a "low espressed spot"?
> > It seems a problem of logic.
>  
> a better way to say it is "low intensity spot". low intesities are usually
> due to low expression of the gene or probe represented by the spot.
> 

As Rafael advices it, "low intensity spot" is a better way to name that.
Keep in mind that low intensities can be caused by things like
bad hydridization conditions, problem in the labelling of the probes
(in some cases (mostly cDNA arrays) labelling is probe sequence dependant),
etc... 



L.