[Bioc-devel] help with Win10 TSL problem?

Egon Willighagen egon@w||||gh@gen @end|ng |rom gm@||@com
Wed Mar 18 19:55:16 CET 2020

Hi all,

in the BridgeDbR package I have a TSL issue, just on Windows10 [0]:

> location <- getDatabase("Bacillus subtilis")
Error in function (type, msg, asError = TRUE)  :
  error:1407742E:SSL routines:SSL23_GET_SERVER_HELLO:tlsv1 alert
protocol version
Calls: getDatabase ... getBridgeNames -> curlPerform -> <Anonymous> -> fun
Execution halted

This method is using the download.file() method (see [1]). I am not sure
what this method uses by default. I have been googling and found a number
of suggestions on how to get RCurl to use other SSL version, such as:

CURL_SSLVERSION_TLSv1_2 <- 1Lopts <- RCurl::curlOptions(  verbose =
TRUE, sslversion = CURL_SSLVERSION_TLSv1_2)download.file(url, file,
mode = "wb", .opts=opts)

But I haven't found something that works. Error messages are very cryptic,
and I'm running out of ideas.

Does someone have a suggestion how to debug this? Maybe even have a

All feedback is very much appreciated!



Hi, do you like citation networks? Already 51% of all citations are
available <https://i4oc.org/> available for innovative new uses
<https://twitter.com/hashtag/acs2ioc>. Join me in asking the American
Chemical Society to join the Initiative for Open Citations too
the RSC and many others already did <https://i4oc.org/#publishers>.

E.L. Willighagen
Department of Bioinformatics - BiGCaT
Maastricht University (http://www.bigcat.unimaas.nl/)
Homepage: http://egonw.github.com/
Blog: http://chem-bla-ics.blogspot.com/
PubList: https://www.zotero.org/egonw
ORCID: 0000-0001-7542-0286 <http://orcid.org/0000-0001-7542-0286>
ImpactStory: https://impactstory.org/u/egonwillighagen

	[[alternative HTML version deleted]]

More information about the Bioc-devel mailing list