[Bioc-devel] Announcement of a new package called bacon

Maarten van Iterson mviterson at gmail.com
Thu Jun 9 15:37:03 CEST 2016

Dear list,

I would like to introduce the package bacon that has been added to
bioconductor just before the release of version 3.3.

bacon can be used to estimate and control for bias and inflation often
present in epigenome- and transcriptome-wide association
studies(EWAS/TWAS). The idea behind bacon is to estimate the empirical null
distribution from the data (using Bayesian statistics) and use the
empirical null i.s.o. a theoretical null for inference. Bacon supports
bias- and inflation-controlled fixed-effect meta-analysis that can be
executed in parallel. A manuscript is available from biorxiv (

Kind regards,

Maarten van Iterson

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