[Bioc-devel] new package: canceR

Tim Triche, Jr. tim.triche at gmail.com
Fri Mar 27 05:20:31 CET 2015


So use mclust to fit a mixture model? 
(for one gene or exprs%*%coefs) e.g. 

mc <- Mclust(exprScoreOrWhatever)
plot( survfit( Surv(EFS, EFSevent) ~ mc$class ) )

This is from memory but done often.
Seems not too hard to add...?

--t

> On Mar 26, 2015, at 9:00 PM, Dario Strbenac <dstr7320 at uni.sydney.edu.au> wrote:
> 
> An analysis that biologists would be interested in is a Kaplan-Meier analysis with a survival time plot. Can the package do this ? It's the most obvious way to integrate gene expression (allow the samples to be put into a low expression and high expression group, based on a threshold) and clinical data, but I don't see how it could be done with canceR.
> 
> --------------------------------------
> Dario Strbenac
> PhD Student
> University of Sydney
> Camperdown NSW 2050
> Australia
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